I've been riding road bikes for more than 20 years now. I'm 6'6" and have had a hard time finding a set up that suits me, especially at high speeds where things tend to get a little squirrelly.
I've ridden Trek, 3 different styles of Bianchi (one of which was a solo coast to coast adventure), and Tomassini. I currently ride a custom Co-motion frame disguised as a Fish Lips which is owned by a good friend of mine.
After trying my hand at with other metals and composites, I don't think I'll ever own a non-steel frame again. I'm probably too much of a traditionalist, but for comfort and performance, that's the bang for my buck.
The 64 cm frame is complimented by a carbon Wound-Up fork and geared out in full Dura Ace. The biggest issue is that, like my music collection, little has been invested into it since I got married 7 years ago. Which has been okay since it's only been ridden about that many times a year since, but as my kids get a little older, I'm holding out hope that this improves.
About the time that I got married, I got connected with a frame builder in Montana who owns a company called Kirk Frames. This guy shares my identical build (tall and skinny) and so I was intrigued on what kind of machine he could put together for me. Well, since I didn't have any complaints about my Fish Lips and lacked the funds to build up a completely new bike, this thing has sat in a frame bag in my garage for 8 years. An unfortunate tragedy.